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Cody J Wenthur, PharmD/PhD

Assistant Professor
Director, MS Program in Psychoactive Pharmaceutical Investigation

Elucidating how monoaminergic and glutamatergic signaling systems interact to support maladaptive learning and synaptic plasticity in the context of substance use disorders and major depressive disorders; Development of novel bioconjugates and antibodies to probe the effects of psychoactive substances, including synthetic cannabinoids, opioids, ketamine, and classical psychedelics;  Identifying immunologic biomarkers of ongoing drug use and vaccine response; Assessing barriers to implementation of novel addiction treatment paradigms, including vaccine-based approaches and medication-assisted psychotherapy


Aug 2018 - Present Assistant Professor
  University of Wisconsin–Madison – Pharmacy Practice Division
  and Pharmaceutical Sciences Division
Aug 2015- July 2018 Postdoctoral Research Fellow
  The Scripps Research Institute, La Jolla – Department of Chemistry
Aug 2011 - Aug 2015 Doctor of Philosophy - Pharmacology
  Vanderbilt University – School of Medicine
Aug 2005 - May 2011 Doctor of Pharmacy
  Purdue University – College of Pharmacy


Highlighted Publications:

Georgieva JV, Katt M, Ye Z, Umlauf BJ, Wenthur CJ, Shusta EV. The 46.1 Antibody Mediates Neurotensin Uptake into the CNS and the Effects Depend on the Route of Intravenous Administration. Pharmaceutics. 2022 Aug 16;14(8):1706. doi: 10.3390/pharmaceutics14081706.

Chitwood C, Haug KL, Wenthur C, Gillis C, Maloney JD, Johnson D. Evaluation of Prescribing Patterns Following Surgical Procedures in Opioid Naïve Patients at a Veterans Affairs Teaching Hospital. Mil Med. 2022 Apr 22:usac106. doi: 10.1093/milmed/usac106.

Navarro G, Rea W, Quiroz C, Moreno E, Gomez D, Wenthur CJ, Casadó V, Leggio L, Hearing MC, Ferré S. Complexes of Ghrelin GHS-R1a, GHS-R1b, and Dopamine D1 Receptors Localized in the Ventral Tegmental Area as Main Mediators of the Dopaminergic Effects of Ghrelin. J Neurosci. 2022 Feb 9;42(6):940-953. doi: 10.1523/JNEUROSCI.1151-21.2021.

Zheng Z, Kyzer JL, Worob A, Wenthur CJ. Family of Structurally Related Bioconjugates Yields Antibodies with Differential Selectivity against Ketamine and 6-Hydroxynorketamine. ACS Chem Neurosci. 2021 Nov 3;12(21):4113-4122. doi: 10.1021/acschemneuro.1c00498.

Banks MI, Zahid Z, Jones NT, Sultan ZW, Wenthur CJ. Catalysts for change: the cellular neurobiology of psychedelics. Mol Biol Cell. 2021 Jun 1;32(12):1135-1144. doi: 10.1091/mbc.E20-05-0340.

Wartenweiler V, Chung G, Stewart A, Wenthur C. Pharmacy stakeholder reports on ethical and logistical considerations in anti-opioid vaccine development. BMC Med Ethics. 2021 Mar 25;22(1):30. doi: 10.1186/s12910-021-00599-2.

Kyzer JL, McGuire M, Park H, Belz TF, Bonakdar R, Janda KD, Wenthur CJ. Anti-Opioid Antibodies in Individuals Using Chronic Opioid Therapy for Lower Back Pain. ACS Pharmacol Transl Sci. 2020 Aug 25;3(5):896-906. doi: 10.1021/acsptsci.0c00057.

Wu S, Frey T, Wenthur CJ. Naloxone acceptance by outpatient veterans: A risk-prioritized telephone outreach event. Res Social Adm Pharm. 2021 May;17(5):1017-1020. doi: 10.1016/j.sapharm.2020.08.010.

Kyzer JL, Wenthur CJ. Classics in Chemical Neuroscience: Buprenorphine. ACS Chem Neurosci. 2020 May 20;11(10):1385-1399. doi: 10.1021/acschemneuro.0c00100.

Worob A, Wenthur C. DARK Classics in Chemical Neuroscience: Synthetic Cannabinoids (Spice/K2). ACS Chem Neurosci. 2020 Dec 2;11(23):3881-3892. doi: 10.1021/acschemneuro.9b00586. 


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