Background: Christine came to the UW School of Pharmacy in 1979 after serving as a faculty member at the State University of New York-Buffalo. She is a clinical investigator with the UW Allergy, Pulmonary, and Critical Care Division, Director of Clinical Research for the Morris Institute of Respiratory Research, and Director of the Anticoagulation Clinic at the William S. Middleton Memorial Veterans Hospital. She serves as a preceptor for the ASHP-accreditated Primary Care Pharmacy Residency at Veterans Hospital, the ASHP Research and Education Foundation Antithrombotic Therapy Training Program, and elective ambulatory clerkships. Dr. Sorkness serves as co-investigator for several research protocols evaluating the efficacy, safety, and prediction of response of therapeutic agents for asthma and allergic diseases. Dr. Sorkness is an investigator with the NHLBI-funded Asthma Clinical Research Network and the Childhood Asthma Research and Education Network and the NIAID-funded Inner-City Asthma Consortium. She is the Senior Associate Director of the University of Wisconsin Institute for Clinical and Translational Research, which houses the Clinical and Translational Service Award from NIRR.

Professional Interests: Co-investigator for several research protocols evaluating the efficacy and safety of therapeutic agents for asthma and allergic diseases

Education:

• BS - State University of New York-Buffalo
• PharmD - State University of New York-Buffalo

• Busse WW, Morgan WJ, Gergen PJ, Mitchell HE, Gern JE, Liu AH, Gruchalla RS, Kattan M, Teach SJ, Pongracic JA, Chmiel JF, Steinbach SF, Calatroni A, Togias A, Thompson KM, Szefler SJ, and Sorkness CA. Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children. N Engl J Med 2011 Mar 17;364(11): 1005-15. PMID: 21410369. PMC Journal-In Process.
• Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske Jr RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Bade E, Covar RA, Friedman NJ, Guilbert TW, Heidarian-Raissy H, Kelly HW, Malka-Rais J, Mellon MH, Sorkness CA, Taussig L. Use of Beclomethasone Dipropionate as Rescue Treatment for Children with Mild Persistent Asthma (TREXA): a Randomised, Double-blind, Placebo-controlled Trial. Lancet 2011 Feb 19; 377 (9766):650-7. Epub 2011 Feb 14. PMID: 21324520. PMC Journal-In Process.
• Weng L, Hollenbeak CS, Mauger DT, Zeiger RS, Paul IM, Sorkness CA, Lemanske RF Jr, Martinez FD, Strunk RC, Szefler SJ, Taussig LM; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Cost-effectiveness Analysis of Fluticasone versus Montelukast in Children with Mild-to-Moderate Persistent Asthma in the Pediatric Asthma Controller Trial. J Allergy Clin Immunol 2011 Jan; 127(1): 161-166, 166.e1. PMID: 21211651. PMC Journal - In Process
• Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF Jr., Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ for the National Heart Lung and Blood Institute?s Asthma Clinical Research Network. A Trial of Clarithromycin for the Treatment of Suboptimally Controlled Asthma. J Allergy Clin Immunol 2010 Oct; 126(4):747-53. PMID: 20920764. PMC Journal - In process.
• Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF Jr., Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, and Bleecker ER, for the National Heart, Lung, and Blood Institute Asthma Clinical Research Network. Tiotropium Bromide Step-up Therapy for Adults with Uncontrolled Asthma. N Engl J Med 2010 Oct 28; 363(18):1715-26. PMID: 20979471. PMCID: PMC 3011177.
• Rabinovich N, Graber NJ, Chinchilli VM, Sorkness CA, Zeiger RS, Strunk RC, Bacharier LB, Martinez FD, Szefler SJ; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Urinary Leukotriene E(4)/Exhaled Nitric Oxide Ratio and Montelukast Response in Childhood Asthma. J. Allergy Clin Immunol. 2010 Sep; 126(3): 545-551. e1-4. Erratumin: J Allergy Clin Immunol 2010 Nov; 126(5):959-61. Dosage error in article text PMID: 20816189. PMC Journal - In Process.
• Anderson SD, Pearlman DS, Rundell KW, Perry CP, Boushey H, Sorkness CA, Nichols S, Weiler JM. Reproducibility of the Airway Response to an Exercise Protocol Standardized for Intensity, Duration, and Inspired Air Conditions, in Subjects with Symptoms Suggestive of Asthma. Respir Res 2010 Sep 1; 11(1):1-12. PMID: 20807446. PMCID: PMC 2939602.
• Matsui EC, Sampson HA, Bahnson HT, Gruchalla RS, Pongracic JA, Teach SJ, Gergen PJ, Bloomberg GR, Chmiel JF, Liu AH, Kattan M, Sorkness CA, Steinbach SF, Story RE, Visness CM on behalf of the Inner City Asthma Consortium. Allergen-specific IgE as a Biomarker of Exposure Plus Sensitization in Inner-City Adolescents with Asthma. Allergy 2010 Nov; 65(11):1414-22. PMID: 20560910. PMC Journal - In Process.
• Simon MR, Chinchilli VM, Phillips BR, Sorkness CA, Lemanske RF Jr, Szefler SJ, Taussig L, Bacharier LB, Morgan W for the Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Forced Expiratory Flow Between 25% and 75% of Vital Capacity and FEV1/Forced Vital Capacity Ratio in Relation to Clinical and Physiological Parameters in Asthmatic Children with Normal FEV1 Values. J Allergy Clin Immunol 2010 Sep; 126(3): 527-534. e1-8. Epub 2010 Jul 16. PMID: 20638110. PMC Journal - In Process
• Liu AH, Zeiger RS, Sorkness CA, Ostrom NK, Chipps BE, Rosa K, Watson ME, Kaplan MS, Meurer JR, Mahr TA, Blaiss MS, Piault-Louis E, McDonald J. The Childhood Asthma Control Test: Retrospective Determination and Clinical Validation of a Cut-Point to Identify Children with Very Poorly Controlled Asthma. J Allergy Clin Immunol 2010 Aug; 126(2): 267-73. 273.e1. Epub 2010 Jul 10. PMID: 20624640. PMC Journal - In Process.
• Teodorescu M, Polomis DA, Hall SV, Teodorescu MC, Gangnon RE, Peterson AG, Xie A, Sorkness CA, Jarjour NN. Association of Obstructive Sleep Apnea Risk with Asthma Control in Adults. Chest 2010; 138(3): 543-550. PMID: 20495105. PMC Journal - In Process.
• Kattan M, Kumar R, Bloomberg GR, Mitchell HE, Calatroni A, Gergen PJ, Kercsmar CM, Visness CM, Matsui EC, Steinbach SF, Szefler SJ, Sorkness CA, Morgan WJ, Teach SJ, Gan VN. Asthma Control, Adiposity, and Adipokines among Inner-City Adolescents. J Allergy Clin Immunol 2010 Mar; 125(3):584-592. PMID: 20226295. PMC Journal - In Process.
• Lemanske RF Jr, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, Covar RA, Guilbert TW, Larsen G, Morgan WJ, Moss MH, Spahn JD, Taussig LM for the Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute. Step-Up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids. N Engl J Med 2010 Mar 18;362(11):975-985. PMID: 20197425. PMCID: PMC 2989902