UW-Madison School of Pharmacy

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Jiaoyang Jiang, PhD

Associate Professor


Our research interests span the gap between biology and chemistry. We are intrigued by the roles of protein post-translational modifications in regulating human physiological and pathological processes. We focus on a unique type of protein glycosylation, termed O-linked β-N-acetylglucosamine (O-GlcNAc). This modification dynamically regulates various biological processes and its dysfunction has been detected in many diseases. Our research program integrates multidisciplinary approaches to elucidate the mechanism and function of this O-GlcNAc modification. Read more...

Dr. Jiaoyang Jiang earned her PhD in chemistry from Brown University with David Cane, where she elucidated natural product biosynthetic pathways in bacteria. Following that, Dr. Jiang performed postdoctoral research at Harvard Medical School in the laboratory of Suzanne Walker, where she characterized the glycosyltransferase & the unique proteolytic activities of human O-GlcNAc transferase (OGT), and discovered a small molecule with novel mechanism of inhibition. In August 2013, Dr. Jiang started her appointment as an Assistant Professor of Drug Discovery at the UW-Madison School of Pharmacy. She was promoted to Associate Professor with tenure in 2019.

Education:

  • Postdoc Chemical Biology - Harvard Medical School, 2013
  • PhD Chemistry - Brown University, 2009
  • BS Chemistry - Univ. of Science & Technology of China, 2004
Highlighted Publications: